Will today be the last game that Andrew Luck is out? Chris Mortensen says he's close to returning:
Andrew Luck expected to begin practicing as early as next week and, barring no setbacks, his return to play is within sight, per sources— Chris Mortensen (@mortreport) September 24, 2017
It's unlikely that Luck will play after just one week of practice, which would scratch him from next week's start in Seattle. However, if the report is true, it appears that a Week 5 return could be in the cards.